ACTION HIV (Anal Cancer TherapIes and Outcomes iNitiative for Patients Living With and Without HIV): A Global Record of Patients With Anal Squamous Cell Carcinoma With and Without HIV Infection

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Due to the scarcity of data on prognostic and predictive influence on CCA, epidemiological studies evaluating these factors need to be developed in patients with CCA. Therefore, the investigators want to evaluate the profile of patients in the real world and from various parts of the world, describing prognostic factors such as CD4 dosage, time of HIV infection, evaluation of viral load, diagnosis of AIDS, geographic region of diagnosis and treatment, clinical staging, medications concomitant with QRT (risk of drug interactions), comorbidities (possible impact on dose-intensity), use of HAART, time of use of HAART, radiotherapy modality (conventional 3D vs Modulated Beam Intensity \[IMRT\], response to Nigro vs CTII regimens, as well as comparing clinical outcomes with patients without HIV infection.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Patients 18 years of age or older

• Confirmed histological diagnosis of anal canal squamous cell carcinoma. Basaloid subtype is accepted

• Have underundered serological test for HIV infection

• Any clinical stage

Locations
Other Locations
Brazil
A.C. Camargo Cancer Center
RECRUITING
São Paulo
Contact Information
Primary
Viviane Horn de Melo
viviane.melo@lacogcancerresearch.org
+55 51 3384 5334
Backup
Laura Voelcker
laura.voelcker@lacogcancerresearch.org
+55 51 3384 5334
Time Frame
Start Date: 2023-06-09
Estimated Completion Date: 2025-04-24
Participants
Target number of participants: 300
Treatments
With HIV Infection
Patients with CCA with HIV infection,
Without HIV Infection
Patients with CCA without HIV infection,
Related Therapeutic Areas
Sponsors
Leads: Latin American Cooperative Oncology Group

This content was sourced from clinicaltrials.gov

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